From 59 South:
Traveling north on U.S. 59 (from the Richmond/Rosenberg area): Exit Highway 6. Turn right on Highway 6, continuing east for approximately 6 miles to Sienna Parkway. Turn right and follow the signs to the Home Finder Center.

From 59 North:
Traveling south on U.S. 59 (from the Galleria or Greenway Plaza area): Take U.S. 59 to Highway 6. Exit Highway 6. Turn left on Highway 6, continuing east for approximately 6 miles to Sienna Parkway. Turn right and follow the signs to the Home Finder Center.

From Hwy. 288 North:
Traveling south on Highway 288 (from the Downtown area): Exit Highway 6. Turn right, continuing west on Highway 6 for 8.5 miles to Sienna Parkway. Turn left and follow the signs to the Home Finder Center.

or

Traveling south on Highway 288 (from the Downtown area): Exit Sam Houston Parkway/Beltway 8. Turn right continuing west for about 6.5 miles to Fort Bend Tollway. Turn left continuing south for about 8 miles to Sienna Parkway, continuing north for 0.25 miles to the Homefinder Center.

From Highway 288 South:
From Highway 288 North (from the Lake Jackson area): Exit Highway 6. Turn left, continuing west on Highway 6 for 8.5 miles to Sienna Parkway. Turn left and follow the signs to the Home Finder Center.

From Houston Medical Center:
From the Medical Center, take Highway 90 South to the Fort Bend Tollway. Turn left on the Fort Bend Tollway continuing south for 8 miles to Sienna Parkway. Turn right on Sienna Parkway continuing 0.25 miles to the Homefinder Center.

An EZ Tag makes a huge difference in drive times. The EZ Tag only toll road, Fort Bend Parkway, is located one mile from the main entrance of Sienna Plantation and will cut many minutes off of your commute to and from the Medical Center. The Fort Bend Parkway also gives an alternate route when commuting to other locations in the Houston area.